PRF - Platelet Rich Fibrin -The leading treatment in regenerative medicine

Platelet Rich Fibrin (PRF) is a second generation PRP and a remarkable advancement in the regenerative medicine field, offering a plethora of benefits for patients seeking a natural approach to healing. Derived from a patient's own blood, PRF is a gel-like substance rich in platelets, growth factors, and fibrin, which play crucial roles in tissue repair and regeneration. PRF treatment is versatile and can be utilized in various medical and dental domains. It is often used to expedite the healing of wounds, improve skin and hair rejuvenation, and aid in the recovery of various orthopedic conditions including joint and tendon injuries.

The beauty of PRF lies in its ability to provide a biological boost to the body's innate healing capacity, all while minimizing the risk of allergic reactions or infections since it's derived from the patient's own blood. Through harnessing the natural healing constituents of the blood, PRF opens new doors to enhancing patient care and recovery across a broad spectrum of treatments.

In PRF  no anticoagulants are added which allows a naturally form of spongy fibrin matrix that signals the platelets to release their growth factors  gradually and extended release of growth factors by platelets and leukocytes entrapped within the fibrin matrix in PRF provide long-lasting results.

Platelet Rich Fibrin For Joints

Platelet Rich Fibrin For Joints

PRF has been used for a variety of medical conditions such as nerve injury, chronic tendon injuries, osteoarthritis, fractures, acute ligament and muscle injuries, cardiac muscle injury, plastic and oral surgery.

Platelet Rich Fibrin (PRF) works for joints by harnessing the natural healing properties of your body's own platelets to promote tissue repair and regeneration. Here's a breakdown of how the process works:

  1. Blood Sample Collection: A small sample of your blood is collected, typically from your arm, using a specialized kit or system designed to concentrate platelets.

  2. Centrifugation: The collected blood sample is then placed in a centrifuge, a machine that spins the blood at high speeds. This process separates the blood components based on their density.

  3. Platelet Concentration: The centrifuge isolates and concentrates the platelets, which contain growth factors and other bioactive proteins essential for healing.

  4. Fibrin Formation: The concentrated platelets are mixed with fibrin, a natural protein involved in blood clotting. This creates a gel-like substance known as Platelet Rich Fibrin.

  5. Injection into the Joint: The prepared PRF is strategically injected into the affected joint. The injection is usually guided by imaging techniques like ultrasound to ensure precision.

  6. Release of Growth Factors: Once injected, the platelets in PRF release a plethora of growth factors, cytokines, and proteins. These substances play a crucial role in stimulating cell growth, collagen production, and tissue repair.

  7. Promotion of Healing: The released growth factors initiate a cascade of biological processes, promoting the healing of damaged tissues, reducing inflammation, and improving overall joint function.

  8. Natural Regeneration: PRF encourages the body's natural regenerative abilities, aiding in the repair of cartilage, ligaments, and other structures within the joint.

  9. Pain Relief and Improved Mobility: As the joint heals and inflammation decreases, patients often experience pain relief and improved mobility. PRF's regenerative effects contribute to the long-term well-being of the joint.

It's important to note that while PRF for joints shows promise in various orthopedic applications, individual results may vary. Consultation with a healthcare professional is essential to determine if PRF is a suitable option for your specific joint condition.

PRF Breast Lift

One of the best non-surgical breast enhancement solutions is the PRF Breast Lift. This alternative breast lift is a non-surgical approach that is natural, safer, and more affordable than surgical options.

The PRF Breast Lift uses your own blood to stimulate new collagen, elastin, fibrin, and adipose tissue development (thus the name!). More specifically, it uses your platelet-rich plasma (PRP) and platelet-rich-fibrin (PRF) to stimulate new tissue development. Your PRF is injected directly into the breast tissue to enhance size and shape, improve cleavage, tighten sagging skin, increase nipple sensitivity, reverse inverted nipples, and correct cosmetic issues resulting from aging breast implants.

**Cost is dependent on how much PRF is needed for your desired outcome**

Platelet Rich Fibrin Frequently Asked Questions

Platelet-rich fibrin can have multiple benefits for osteoarthritis of the knee. Along with improving growth in arthritic cartilage, PRF for osteoarthritis can:

 
  • Reduce pain and inflammation caused by osteoarthritis: The PRF injection knee treatment can help reduce pain and inflammation that is caused by osteoarthritis and other bone issues by lessening the overall stress on your joints.

  • Activate stem cells and increase growth and repair of damaged tissue: PRF injection treatments have been shown to activate stem cells and increase growth and repair of damaged tissue. The PRF procedure involves the use of concentrated platelets, which have been known to improve overall functions and processes in the body.

  • Slow progression of osteoarthritis while improving current discomfort: PRF can also improve discomfort caused by osteoarthritis. 

 

A study conducted by the Hospital for Special Surgery in New York also showed that PRP injection knee treatments improved overall pain and knee function in up to 73% of patients and slowed the progression of osteoarthritis. RP has some very promising results however more research studies are needed to back up the clinical results.

The risks of PRF are minimal. There is always a small risk of infection with any injection and some patients may experience some pain and/or inflammation at the injection site. 

The number of injections varies depending upon the site being injected. Usually patients being treated for OA of the knee will receive 2-3 injections done 2-4 weeks apart.

Stop all anti-inflammatory medications for 2 weeks prior to injections (e.g. Advil, ASA, Aleve, Naprosyn, Voltaren, Arthrotec, and Celebrex.) 

 

Patients MUST INFORM THE NP if:

 
  1. You are on anti-coagulation therapy such as Coumadin, Plavix, Pradax, Low molecular weight heparin 

  2. You are Pregnant

  3. You have an active infection at the injection site

  4. You have a local tumour at the site of injection

  5. You have metastatic disease (cancer).

It is generally a good idea to avoid any strenuous activities for a few days after the PRF. Only resume sporting activities if you are pain free with activities of daily living. Individuals taking anti-inflammatories should wait 1 week after their complete course of PRP treatments before resuming.

Most people start experiencing a response 2-3 weeks after the final injection.

I'd Like to Learn More About Platelet Rich Fibrin

If you'd like to learn more about how PRF could benefit you and your unique needs, contact us for a consultation. We'll review your needs and create a tailored treatment plan to reach your goals.